Life Extension, SAMe (S-Adenosyl-L-Methionine), 400 mg, 60 Enteric Coated TabletsS Adenosyl Methionine Supports Joints and Emotional Well Being Dietary Supplement SAMe has multiple mechanisms of action that are used throughout the body Brain and Mood SAMe boosts brain cell methylation and facilitates youthful DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters such as norepinephrine, dopamine, and seratonin and may account for SAMe's mood elevating properties. SAMe also helps