Pigmentbio Night Renewer CreamBioderma Pigmentbio Night Renewer Cream is a brightening overnight cream designed for skin prone to pigmentation problems. The cream features an active ingredient, hexapeptide 2, that stimulates collagen production and helps to make the skin smoother in the morning. The cream helps to reduce the appearance of dark spots, prevents new darkness from appearing, and illuminates and unifies skin tones.